what is purines nucleotides - Water Use in Gout Treatment - it Dissolves More Uric Acid
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Water Use in Gout Treatment - it Dissolves More Uric Acid

Just about anyone who suffers from gout knows that they should be drinking a lot of water every day. I will come on to why in a moment but first, for any gout sufferer who does not know the basics, here they are.


MAKING ALKALINE WATER Most people are not able to buy alkaline water at their local supermarket or grocery store. You have to make it yourself. It's not difficult. Basically you can either add alkaline drops to regular water or you can have a water ionizer do it for you. Alkaline drops can be purchased via the Internet and delivered to you, search alkaline water drops, or alkaline drops.


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 Until research revealed something... Research Tested Natural Remedies Only in the last decade has natural health began to surge because of research. Numerous research studies have shown that some century-old gout natural cures have been extremely effective in treating gout and lowering uric acid levels (the cause of gout).

But don't expect your doctor to tell you about these secrets. If they did, pharmaceutical companies would lose billions of dollars annually. The medical community (hospitals and pharmacies) would never allow this to happen! But natural health doctors would and here is what they suggest!

NB. The contents of this article contain medical information, not medical advice. Please always discuss gout remedies with your doctor or other health care professional before implementing any treatment.

Caution! Just as a highly acidic body can suffer from acidosis, an over alkaline body can suffer from alkalosis. This causes muscle cramps and spasms among other problems. So do not over do it. As always when dealing with gout, work with your doctor, or other health care professional.

We promise you will not be disappointed in curing gout at home!

Other encouraging statements were that all extension trial patients who had responded earlier to treatment and who were on the every two week course maintained normal uric acid levels, (some were new joiners). 70% of those on an every four week course who had responded earlier to treatment, maintained normal uric acid levels.

There are other ways of raising pH (a diet containing lots of alkaline effect foods and less acid effect foods, alkaline water, baking soda (bicarbonate of soda), but water is just about the cheapest.

Gout is one of the most painful forms of arthritis! And these natural remedy gout secrets have been used for centuries. However, they seemed to be forgotten in the last fifty years after various synthetic medications have entered the health scene. Natural remedies were a thing of the past until 10 years ago!

After a period of drinking alkaline water your body pH should rise. How will you know? Saliva pH can be tested with pH test strips (search pH test strips or pH stix). Your saliva pH is a good indication of your body's pH levels. Make sure you follow the manufacturer's instructions for using them carefully. Record numbers and watch for trend changes over time. A few tests are not enough.

1. Purine Levels- You should learn what purines are! Purines cause a rise in uric acid levels which cause gout flare-ups. You should avoid eating large quantities of meat. We recommend only eating 6 ounces of meat, fish or poultry per day. Find other sources for protein until you normalize your uric acid levels.

31% of patients who had not reduced tophi at the end of these phase 3 trials did show tophi reduction in the extension trial. It would seem that the longer a gout sufferer is able to take Pegloticase the more successful it may be, in tophi cases at least.

2. What You Drink- This can have a great effect on your uric acid levels. Uric acid can be flushed by drinking at least 10 glasses of water a day. Or uric acid levels can jump through the roof by drinking more than 2 alcoholic beverages a day. Women are recommended to only drink one per day.

TRIAL SUCCESS WITH DIFFICULT TO TREAT GOUT PATIENTS Pegloticase is significant because its trials have focused on gout patients who have not had success with other gout drugs, or who have medical conditions which prohibit the use of them. Thus it has been tackling harder-to-treat gout cases, not the easier ones. Hard to treat cases are a significant percentage of the gout sufferer universe.

In the world of natural gout remedies, uric acid's removal can be improved by making it more soluble. This is achieved by drinking lots of water and by raising body pH levels in various ways.

I discussed the value of drinking water in natural gout treatment in earlier articles. Of course all types of water are not equal, for example hard water is better than soft because of its additional mineral content and distilled water is acidic. Probably the best of all waters for natural gout treatment is alkaline water, also called ionized water.

Pegloticase is getting closer to an application for approval by the U.S. FDA. Its developers hope to apply for a Biologics Licence Application in September 2008, and begin marketing it in 2009.

Therefore, the ''trick'' in curing gout is to remove uric acid. However, there are other natural ways of assisting the removal of uric acid, and just about the most popular, to judge from views of online polls I have seen, is drinking water. How does water work? Simply because a hydrated body will dilute uric acid and diluted uric acid is more likely to be excreted. This is the first reason why water use in gout treatment is so important.

How much water a day? The quoted amount varies from 8 to 12 of 8 fl.ozs glasses a day. But perhaps the true amount for you is the amount of water you need to raise the body pH above 7.0. How can you know your pH level? pH test strips can be purchased online and delivered by mail. Type '' pH test strips" or "pH test stix" into a search box. Make sure you follow precisely the manufacturers' instructions in the accompanying leaflet.

Pegloticase's answer to the excess uric acid level problem is to remove it by ingeniously converting uric acid into something else, a substance called Allantoin. Allantoin is more soluble and better excreted than uric acid. The principle comes from the way most animals do it. They do it by converting UA to Allantoin, but this is something humans cannot do naturally. Hence the formulation of Pegloticase.

HOW PEGLOTICASE WORKS What makes Pegloticase a very interesting, and more importantly, a hopeful new gout drug, is the way it works. All drugs used in gout try to cure or alleviate the disease by reducing the body's uric acid (UA) levels. They do this by either inhibiting its production or making it easier to remove.

Hopefully these indicate that the theory has indeed shaken hands with the practice, and the rejoicing is happily justified. Most gout sufferers hope for a natural remedy for gout. Taking account of pH is part of natural gout treatment.

Will any water do? Yes, but some kinds are better than others are. Hard water is better than soft water because it contains more minerals. So too does mineral water. Minerals help maintain the body pH at 7.0 or greater. What is pH? This is a measurement of the acid/alkaline balance of the body. A pH of 7.0 or higher means a more alkaline body; below 7.0 and its more acidic.

In other patient groups there were reductions in attacks and improvement in tophi reduction. Tophi are those knobbly shaped, awkward looking, lumps of MSU crystals that often develop in longer term gout sufferers.

3. Being Active- Do you know that being active and exercising has been shown to have hundreds of benefits, including curing gout. When you are over your ideal body weight, your body will retain more uric acid and also put more pressure on joints. This is the perfect combination to cause repeated gout flare-ups. Our gout remedy report suggests some simple tips to lose 20 pounds or more.

IONIZERS ARE BETTER THAN DROPS As well as being cheaper than drops, ionizers can be adjusted to produce a water pH of a specific value more accurately. Set it to pH 8.5 or pH 9.0 for example. They can also produce purified water and leave you with acidic water, which has its uses. Moreover, the best water ionizers adjust for the overall quality of water supply input. By so doing, they produce a correct pH level, irrespective of water supply quality, water pressure and flow rate.

Get Relief in an Hour Those 4 gout natural cures secrets will eventually treat your gout permanently. But what about your pain right now? You can actually get relief in one hour too! All you need to know is what simple ingredient (most likely in your cupboard right now) neutralizes the uric acid in minutes. And this alkaline ingredient can work during any flare-up!

 
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If you are serious about treating gout, please visit our Gout Natural Cures website today. We offer the only research-based, step by step, medical doctor approved Gout Natural Remedy Report that has helped thousands. And due to our overwhelmingly high success rate, we are now offering a 6 month guarantee on our remedy report. To have our report sent to your computer in minutes, please visit us today!

Testimonials from gout sufferers, (one is a doctor), about the value of alkaline water can be read at http://www.ionizers.org/alkalife-testimonials.html and at http://www.waterionizer.org/site/898596/page/443030#33

How can you be certain that you have met your daily water target? Counting your score of water drunk every day is boring and prone to memory lapses. So use this tip. Every evening, or early in the morning, fill a jug with 8 x 8 fl.ozs of water (64 fl.ozs). Alternatively, the amount you have decided on, such as two jugs each of 4 x 8 fl.ozs of water and 4 x 8 fl.ozs of juice; or one jug of 10 x 8 fl.ozs of water and so forth. Use this source to make your other water based drinks that count as water intake.

Gout Natural Cures Tested by Kings Gout was once known as the disease of kings. This is because gout is usually caused by a king-like lifestyle including a poor diet, alcohol and an inactive lifestyle. Here are age-old tips for gout that have shown to be valid.

4. Vitamin Therapy- Are you taking your vitamins? Studies have shown that a deficiency in vitamins such as A, B5 and E are serious factors that can lead to the formation and advancement of gout symptoms. You should find a quality vitamins distributor today.

Why is a higher pH desirable for gout sufferers? Because at a higher pH (i.e. the body is more alkaline) more uric acid is likely to be excreted too. This is the second reason why gout sufferers need to drink lots of water.

A natural gout remedy, as with all gout treatments, requires the reduction of uric acid levels. The normal clinical target is a serum (blood) level of 6 mg/dL for men, less for women. Reducing uric acid to these levels often dissolves the MSU crystals which are mainly formed from uric acid. (The immune system's reaction to these crystals is the immediate cause of pain and inflammation). Drugs such as Allopurinol (generic name) are xanthine oxidase inhibitors -- Allopurinol inhibits the enzyme which is needed for a major part of the process of converting purines into uric acid in the liver, and so less uric acid is produced. Drugs such as Probenecid (generic name) and Sulfinpyrazone (generic name) aid its excretion.

It has been having a decent degree of success. Elimination of gout attacks In its most recent statement the developing company's most significant remark was that the extension trial group receiving Pegloticase every two weeks, there were only four gout attacks among those who had been administered Pegloticase (8 mg) every fortnight for two months, in subsequent months. And none in this group had a gout attack after five months of Pegloticase treatment, in following months. All were patients who had been through a phase 3 trial.

ALKALINE WATER TESTIMONIALS Testimonials from delighted former gout sufferers can be found in many places on the Internet. Unfortunately they are not everything for every gout sufferer because gout is a complicated, still not wholly understood disease, and because what works for one sufferer may not work for others.

SIDE EFFECTS Of course Pegloticase has caused side effects, in the extension trial in about 1 in 5 patients. The developing company has said that most were mild, moderate, or controllable. But in some cases more severe side effects have been described as including chest and back pains, muscle cramps, sweating and flushes.

John Mepham has spent much time researching gout. His best tip for curing gout naturally? Get to your ideal weight whatever the sacrifices may be. Learn more about natural gout treatment at this e-book which has an an emphasis on natural gout treatment

Ionizers are easily installed to your faucet (tap). Most people will not need a plumber or next door neighbour. The ionizers of course cost more, but the water they produce is cheaper over time, say the manufacturers of one leading brand, than buying bottled water of various kinds. So it will pay in the end to think long term and fork out more cash. For a quality ionizer expect to pay from US$769 to US$2,495 for a top-of-the-range-model. (These are U.S. prices. Prices will vary in other countries). You also need to replace the ionizer's biostone filter about every nine months. Filters cost from US$55 to US$85. The ionizer may last up to 20 years.

This suggests that progression of the disease may be contained in difficult-to-treat cases, and therefore may not cause other medical conditions such as kidney stones heart disease and hypertension.

May was a good month for gout sufferers. Febuxostat, (EU trade/brand name Adenuric), the first new major drug medication for gout in over 40 years, was approved for marketing in member countries of the European Union.

Water itself has a pH of 7.0 so it helps to raise the body pH to 7.0, or more when used in conjunction with other alkalizing agents. Occasionally you will see bottled water labels state this 7.0 value, just about the only product in the supermarket that states its pH value. Foods do have a pH value which means that some foods make the body more alkaline and some more acidic.

Moreover, however sincerely meant, and truthfully stated, testimonials may not be accurate in the long term because gout can go into remission and lie low for a long period before flaring up again. On the other hand there are testimonials from people who have not had a gout attack for 1-2 years or more, and this probably indicates a cure has been achieved.

Put the jug the refridgerator. Use only this jug for your drinking water and other relevant beverages. If you are traveling, or drink water at a place of employment, take your water supply in another container only from this jug. When refilling the jug in the evening (or in the early morning) make sure the jug is empty. This means that you drank your daily gout diet requirement without having to count every glass.

Hundreds of Dollars! That is how much money you can save by these gout natural cures secrets. And just think you could also save yourself pain and the time to visit the doctor only to be recommended various pain killers.

In May 2008 the U.S. based company developing Pegloticase made another upbeat statement assessment of what they have learnt in its Phase 3 and open label extension trials. Note that Pegloticase still awaits approval from medical authorities so I am writing here about a new gout drug that is still under development.

The reason is that alkaline water has a higher pH value than other kinds. Alkaline water is water with more oxygen, in this case OH-, not O2. Drinking it makes the body more alkaline. In this state, the body is likely to excrete more uric acid. Reducing uric acid levels to below 6.0 mg/dL (men), slightly less in women, is the target of most forms of gout treatment whether drug medications or natural remedies. Alkaline water is also an antioxidant which squelches free radicals.

NB. The contents of this article contain medical information not medical advice. Please always discuss gout remedies with your doctor or other health care professional, before implementing any treatment.


 
 
     
 
 





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